Hidekazu Shirota: search on Z-Library

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1

Recent progress concerning CpG DNA and its use as a vaccine adjuvant

Shirota, Hidekazu, Klinman, Dennis M

Journal:

Expert Review of Vaccines

Year:

2014

Language:

english

File:

PDF, 409 KB

english, 2014

2

Immunostimulatory CpG oligonucleotides: Effect on gene expression and utility as vaccine adjuvants

Dennis M. Klinman, Sven Klaschik, Koji Tomaru, Hidekazu Shirota, Debra Tross, Hidekazu Ikeuchi

Journal:

Year:

2010

Language:

english

File:

PDF, 810 KB

english, 2010

3

CD2AP Expression in a Renal Ischemia/Reperfusion Injury Model and Analysis of Its Related Genes Using Overexpression and RNA Interference Technique

Nishimura, Sayoko, Yoshida, Takumi, Sugiura, Hidekazu, Shirota, Satsuki, Tsuchiya, Ken, Nihei, Hiroshi

Journal:

American Journal of Nephrology

Year:

2005

Language:

english

File:

PDF, 516 KB

english, 2005

4

The characteristics of relapse in adult-onset minimal-change nephrotic syndrome

Takashi Takei, Minako Koike, Koichi Suzuki, Satsuki Shirota, Mitsuyo Itabashi, Shigeru Ohtsubo, Hidekazu Sugiura, Keiko Suzuki, Chiari Kojima, Masaki Takahashi, Jun Ino, Tetsuya Ogawa, Keiko Uchida, K

Journal:

Clinical and Experimental Nephrology

Year:

2007

Language:

english

File:

PDF, 220 KB

english, 2007

5

PL3-5 A novel role of IL-22R1 as a possible driver of inflammation in ALK+ anaplastic large cell lymphoma

Ram Savan, Della A. Reynolds, Adelle P. McFarland, Lionel Feigenbaum, Karthika Ramakrishnan, Hidekazu Shirota, Dennis M. Klinman, Kieron Dunleavy, Stefania Pittaluga, Stephen K. Anderson, Raymond P. D

Journal:

Year:

2010

Language:

english

File:

PDF, 36 KB

english, 2010

6

CS1-2 Targeted removal of IFN-gamma 3′untranslated region AU-rich element alters B cell function resulting in lupus-like disease in C57BL6 mice

Deborah L. Hodge, Cyril Berthet, Jeff Subleski, Vincenzo Coppola, Hidekazu Shirota, Matthew Buschman, Catherine Razzook, Howard A. Young

Journal:

Year:

2010

Language:

english

File:

PDF, 133 KB

english, 2010

7

IFN-gamma AU-rich element removal promotes chronic IFN-gamma expression and autoimmunity in mice

Hodge, Deborah L., Berthet, Cyril, Coppola, Vincenzo, Kastenmüller, Wolfgang, Buschman, Matthew D., Schaughency, Paul M., Shirota, Hidekazu, Scarzello, Anthony J., Subleski, Jeff J., Anver, Miriam R.,

Journal:

Journal of Autoimmunity

Year:

2014

Language:

english

File:

PDF, 3.86 MB

english, 2014

8

Efficacy and Safety of Carboplatin and Etoposide Combination Chemotherapy for Extrapulmonary Neuroendocrine Carcinoma: A Retrospective Case Series

Imai, Hiroo, Shirota, Hidekazu, Okita, Akira, Komine, Keigo, Saijo, Ken, Takahashi, Masahiro, Takahashi, Shin, Takahashi, Masanobu, Shimodaira, Hideki, Ishioka, Chikashi

Journal:

Year:

2015

Language:

english

File:

PDF, 418 KB

english, 2015

9

Blockade of TNFR2 signaling enhances the immunotherapeutic effect of CpG ODN in a mouse model of colon cancer

Nie, Yingjie, He, Jiang, Shirota, Hidekazu, Trivett, Anna L., Yang, De, Klinman, Dennis M., Oppenheim, Joost J., Chen, Xin

Journal:

Science Signaling

Year:

2018

Language:

english

File:

PDF, 1.10 MB

english, 2018

10

P1-12-2A RETROSPECTIVE ANALYSIS OF THE EFFICACY AND SAFETY OF REGORAFENIB IN PATIENTS WITH CHEMO-REFRACTORY COLORECTAL CANCER

Oishi, Takayuki, Takahashi, Masanobu, Shiono, Masatoshi, Takahashi, Shin, Akiyama, Shoko, Shirota, Hidekazu, Shimodaira, Hideki, Kato, Shunsuke, Ishioka, Chikashi

Journal:

Annals of Oncology

Year:

2014

File:

PDF, 57 KB

2014

11

Therapeutic Potential of Oligonucleotides Expressing Immunosuppressive TTAGGG Motifs

DENNIS M. KLINMAN, IHSAN GURSEL, SVEN KLASCHIK, LI DONG, DEBBIE CURRIE, HIDEKAZU SHIROTA

Journal:

Annals of the New York Academy of Sciences

Year:

2005

Language:

english

File:

PDF, 75 KB

english, 2005

12

Use of CpG oligonucleotides for cancer immunotherapy and their effect on immunity in the tumor microenvironment

Shirota, Hidekazu, Klinman, Dennis M

Journal:

Year:

2013

Language:

english

File:

PDF, 699 KB

english, 2013

13

Successful sequential treatment of a patient with advanced gastrointestinal stromal tumor using four different molecularly targeted drugs

Sugiyama, Shunsuke, Ishizuka, Mariko, Takahashi, Masanobu, Komine, Keigo, Imai, Hiroo, Saijo, Ken, Takahashi, Masahiro, Shirota, Hidekazu, Takahashi, Shin, Shimodaira, Hideki, Ishioka, Chikashi

Journal:

International Cancer Conference Journal

Year:

2016

Language:

english

File:

PDF, 590 KB

english, 2016

14

Therapeutic Applications and Mechanisms Underlying the Activity of Immunosuppressive Oligonucleotides

Dennis M. Klinman, Debbie Tross, Sven Klaschik, Hidekazu Shirota, Takeshi Sato

Journal:

Annals of the New York Academy of Sciences

Year:

2009

Language:

english

File:

PDF, 119 KB

english, 2009

15

Alteration of Anionic Sites in Renal Glomerular Basement Membrane of Pigs.

SHIROTA, Kinji, TANAKA, Hidekazu, SUGIMOTO, Jiro, NOMURA, Yasuo

Journal:

Journal of Veterinary Medical Science

Year:

1997

Language:

english

File:

PDF, 122 KB

english, 1997

16

Contribution of interferon-β to the immune activation induced by double-stranded DNA

Hidekazu Shirota, Ken J. Ishii, Hiroki Takakuwa, Dennis M. Klinman

Journal:

Year:

2006

Language:

english

File:

PDF, 317 KB

english, 2006

17

FDA guidance on prophylactic DNA vaccines: Analysis and recommendations

Dennis M. Klinman, Sven Klaschik, Debra Tross, Hidekazu Shirota, Folkert Steinhagen

Journal:

Year:

2010

Language:

english

File:

PDF, 139 KB

english, 2010

18

MO2-1-6Adoption of multigene panel testing for hereditary cancer "CancerNext" in Tohoku University Hospital

Komine, Keigo, Takahashi, Masanobu, Hiraide, Sakura, Yamada, Hideharu, Tsubata, Mari, Takahashi, Masahiro, Takahashi, Shin, Shirota, Hidekazu, Niihori, Tetsuya, Aoki, Yoko, Ishioka, Chikashi

Journal:

Annals of Oncology

Year:

2019

File:

PDF, 78 KB

2019

19

Production and Pharmacologic Modulation of the Granulocyte-Associated Allergic Responses to Ovalbumin in Murine Skin Models Induced by Injecting Ovalbumin-Specific Th1 or Th2 Cells

Terui, Tadashi, Okada, Mikiko, Honda, Motoko, Ozawa, Maki, Tagami, Hachiro, Sano, Kunio, Shirota, Hidekazu, Hirasawa, Noriyasu, Tamura, Gen

Journal:

The Journal of Investigative Dermatology

Year:

2001

Language:

english

File:

PDF, 355 KB

english, 2001

20

188 Synergistic up-regulation of cytokine encoding genes by CpG oligonucleotides plus poly (I:C)

Lev Petrenko, Sven Klaschik, Hidekazu Shirota, Dennis M. Klinman

Journal:

Year:

2008

Language:

english

File:

PDF, 45 KB

english, 2008

21

Short- and long-term changes in gene expression mediated by the activation of TLR9

Sven Klaschik, Debra Tross, Hidekazu Shirota, Dennis M. Klinman

Journal:

Molecular Immunology

Year:

2010

Language:

english

File:

PDF, 1.38 MB

english, 2010

22

Regulation of T-helper Type 2 Cell and Airway Eosinophilia by Transmucosal Coadministration of Antigen and Oligodeoxynucleotides Containing CpG Motifs

Shirota, Hidekazu, Sano, Kunio, Kikuchi, Tadashi, Tamura, Gen, Shirato, Kunio

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2000

Language:

english

File:

PDF, 205 KB

english, 2000

23

Transforming Growth Factor- β Secreted from CD4 + T Cells Ameliorates Antigen-Induced Eosinophilic Inflammation

Haneda, Kanna, Sano, Kunio, Tamura, Gen, Shirota, Hidekazu, Ohkawara, Yuichi, Sato, Takehito, Habu, Sonoko, Shirato, Kunio

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

1999

Language:

english

File:

PDF, 123 KB

english, 1999

24

Antibiotics Improve the Treatment Efficacy of Oxaliplatin-Based but Not Irinotecan-Based Therapy in Advanced Colorectal Cancer Patients

Imai, Hiroo, Saijo, Ken, Komine, Keigo, Yoshida, Yuya, Sasaki, Keiju, Suzuki, Asako, Ouchi, Kota, Takahashi, Masahiro, Takahashi, Shin, Shirota, Hidekazu, Takahashi, Masanobu, Ishioka, Chikashi

Journal:

Journal of Oncology

Year:

2020

File:

PDF, 1.54 MB

2020

25

Effect of CpG ODN on monocytic myeloid derived suppressor cells

Shirota, Hidekazu, Klinman, Dennis M.

Journal:

Year:

2012

Language:

english

File:

PDF, 965 KB

english, 2012

26

Risk Factors for Progression in Patients with Early-stage Chronic Kidney Disease in the Japanese Population

Yoshida, Takumi, Takei, Takashi, Shirota, Satsuki, Tsukada, Misao, Sugiura, Hidekazu, Itabashi, Mitsuyo, Ogawa, Tetsuya, Uchida, Keiko, Tsuchiya, Ken, Nitta, Kosaku

Journal:

Internal Medicine

Year:

2008

Language:

english

File:

PDF, 219 KB

english, 2008

27

IL4 from T Follicular Helper Cells Downregulates Antitumor Immunity

Shirota, Hidekazu, Klinman, Dennis M., Ito, Shuku-ei, Ito, Hiroyasu, Kubo, Masato, Ishioka, Chikashi

Journal:

Cancer Immunology Research

Year:

2017

Language:

english

File:

PDF, 3.17 MB

english, 2017

28

IL-4 blockade alters the tumor microenvironment and augments the response to cancer immunotherapy in a mouse model

Ito, Shuku-ei, Shirota, Hidekazu, Kasahara, Yuki, Saijo, Ken, Ishioka, Chikashi

Journal:

Cancer Immunology, Immunotherapy

Year:

2017

Language:

english

File:

PDF, 1.34 MB

english, 2017

29

CS13-7. Loss of Ifn-g 3’Untranslated Region Au-rich Element Affects b220+ b Cell and Plasmacytoid Dendritic cell Populations in a Novel Murine Lupus Model

Deborah L. Hodge, Cyril Berthet, Vincenzo Coppola, Hidekazu Shirota, Della Reynolds, Dennis M. Klinman, Howard A. Young

Journal:

Year:

2011

Language:

english

File:

PDF, 45 KB

english, 2011

30

120

Hodge, Deborah L., Berthet, Cyril, Coppola, Vincenzo, Shirota, Hidekazu, Reynolds, Della, Sanford, Michael, Lin, Fanching, Klinman, Dennis M., Young, Howard A.

Journal:

Year:

2013

Language:

english

File:

PDF, 42 KB

english, 2013

31

Efficacy and Safety Assessment of Paclitaxel in Patients with Docetaxel-Resistant Esophageal Squamous Cell Carcinoma

Imai, Hiroo, Komine, Keigo, Takahashi, Shin, Saijo, Ken, Okada, Yoshinari, Kobayashi, Akihiro, Okita, Akira, Chikamatsu, Sonoko, Kasahara, Yuki, Takahashi, Masahiro, Oishi, Takayuki, Shirota, Hidekazu

Journal:

Year:

2016

Language:

english

File:

PDF, 397 KB

english, 2016

32

Predictive factors for the efficacy of the second taxane treatment in patients with advanced cancer

Imai, Hiroo, Saijo, Ken, Komine, Keigo, Kawamura, Yoshifumi, Hiraide, Sakura, Umegaki, Sho, Okada, Yoshinari, Ouchi, Kota, Sato, Yuko, Takahashi, Masahiro, Takahashi, Shin, Shirota, Hidekazu, Takahash

Journal:

Cancer Management and Research

Year:

2018

Language:

english

File:

PDF, 397 KB

english, 2018

33

CpG-conjugated apoptotic tumor cells elicit potent tumor-specific immunity

Hidekazu Shirota, Dennis M. Klinman

Journal:

Cancer Immunology, Immunotherapy

Year:

2011

Language:

english

File:

PDF, 582 KB

english, 2011

34

Efficacy and safety of gemcitabine plus docetaxel in Japanese patients with unresectable or recurrent bone and soft tissue sarcoma: Results from a single-institutional analysis

Takahashi, Masanobu, Komine, Keigo, Imai, Hiroo, Okada, Yoshinari, Saijo, Ken, Takahashi, Masahiro, Shirota, Hidekazu, Ohori, Hisatsugu, Takahashi, Shin, Chiba, Natsuko, Mori, Takahiro, Shimodaira, Hi

Journal:

Year:

2017

Language:

english

File:

PDF, 965 KB

english, 2017

35

Contribution of Fcγ receptor IIB to creating a suppressive tumor microenvironment in a mouse model

Kasahara, Yuki, Shirota, Hidekazu, Umegaki, Sho, Ishioka, Chikashi

Journal:

Cancer Immunology, Immunotherapy

Year:

2019

File:

PDF, 1.18 MB

2019

36

Thickness Changes of Crosslinked Poly(allyltrimethylammonium chloride) Gel Membranes Induced by a Periodic Voltage Change.

IWAMOTO, Kazutoshi, INOUE, Shingo, OGINO, Miharu, SHIROTA, Akihiro, TAJIMA, Hidekazu

Journal:

NIPPON KAGAKU KAISHI

Year:

2002

File:

PDF, 500 KB

2002

37

CpG Oligodeoxynucleotides as a Future Vaccine for Allergic Diseases

Sano, Kunio, Shirota, Hidekazu

Journal:

Allergology International

Year:

2005

Language:

english

File:

PDF, 552 KB

english, 2005

38

Oxidative Stress Decreases Klotho Expression in a Mouse Kidney Cell Line

Mitobe, Michihiro, Yoshida, Takumi, Sugiura, Hidekazu, Shirota, Satsuki, Tsuchiya, Ken, Nihei, Hiroshi

Journal:

Nephron Experimental Nephrology

Year:

2005

Language:

english

File:

PDF, 362 KB

english, 2005

39

A phase 2 basket trial of combination therapy with trastuzumab and pertuzumab in patients with solid cancers harboring human epidermal growth factor receptor 2 amplification (JUPITER trial)

Takahashi, Kenta, Ishibashi, Eri, Kubo, Toshio, Harada, Yohei, Hayashi, Hideyuki, Kano, Masayuki, Shimizu, Yasushi, Shirota, Hidekazu, Mori, Yukiko, Muto, Manabu, Ishioka, Chikashi, Dosaka-Akita, Hiro

Journal:

Medicine (Williams & Wilkins)

Year:

2020

File:

PDF, 238 KB

2020

40

Contribution of IRF-3 mediated IFNβ production to DNA vaccine dependent cellular immune responses

Hidekazu Shirota, Lev Petrenko, Toshio Hattori, Dennis M. Klinman

Journal:

Year:

2009

Language:

english

File:

PDF, 527 KB

english, 2009

41

CpG Oligonucleotides as Cancer Vaccine Adjuvants

Shirota, Hidekazu, Tross, Debra, Klinman, Dennis

Journal:

Year:

2015

Language:

english

File:

PDF, 318 KB

english, 2015

42

Attainment of a Long-term Favorable Outcome by Sunitinib Treatment for Pancreatic Neuroendocrine Tumor and Renal Cell Carcinoma Associated with von Hippel-Lindau Disease

Kobayashi, Akihiro, Takahashi, Masanobu, Imai, Hiroo, Akiyama, Shoko, Sugiyama, Shunsuke, Komine, Keigo, Saijo, Ken, Takahashi, Masahiro, Takahashi, Shin, Shirota, Hidekazu, Sato, Naomi, Fujishima, Fu

Journal:

Internal Medicine

Year:

2016

Language:

english

File:

PDF, 2.15 MB

english, 2016

43

Therapeutic Benefits of Ipilimumab among Japanese Patients with Nivolumab-Refractory Mucosal Melanoma: A Case Series Study

Saijo, Ken, Imai, Hiroo, Ouchi, Kota, Okada, Yoshinari, Sato, Yuko, Komine, Keigo, Takahashi, Masahiro, Takahashi, Shin, Shirota, Hidekazu, Takahashi, Masanobu, Ishioka, Chikashi

Journal:

The Tohoku Journal of Experimental Medicine

Year:

2019

Language:

english

File:

PDF, 1.04 MB

english, 2019

44

Antibiotic therapy augments the efficacy of gemcitabine-containing regimens for advanced cancer: a retrospective study

Imai, Hiroo, Saijo, Ken, Komine, Keigo, Otsuki, Yasufumi, Ohuchi, Kota, Sato, Yuko, Okita, Akira, Takahashi, Masahiro, Takahashi, Shin, Shirota, Hidekazu, Takahashi, Masanobu, Ishioka, Chikashi

Journal:

Cancer Management and Research

Year:

2019

File:

PDF, 453 KB

2019

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